lymphoma treatment | Complications of the disease complications likely to occur during non-Hodgkin malignant lymphomas are as follows:

Lymphoma: Treatment

Treatment the treatment requires of course the determination of the histological type (the type of cells in question) and immunological, and above all the assessment of the extension (more or less complete invasion of the organism by the diseased cells).

The general condition of the patient, also conditions the treatment.

Since the advent of chemotherapy (cyclophosphamide, vincristine, Prednisolone, doxorubicin, etc.), the prognosis of this disease has improved markedly, and in almost 80% of patients, no recurrence has been observed.
Reinjection of bone marrow, and blood peripheral stem cells obtained by cytaphérèse, has also improved the prognosis of this pathology. Radiotherapy i.e. the use of X-rays as a treatment performed above and below the diaphragm on a very wide plane, coupled with chemotherapy also improves the prognosis.
The use of interferon alpha for low-malignancy lymphomas, or in the case of infection, associated with the hepatitis C virus has also shown promising results.
The rituximab-type monoclonal antibody, in the case of low-malignancy non-Hodgkin's lymphoma, has also been tested by some hematology teams in large specialized centres.
The grafting of autologous stem cells in cases of lymphoma of high malignancy or low malignancy with bone marrow invasion was also attempted.
Hematopoietic stem cell transplantation is used to try to overcome certain pathologies, malignant lymphomas not Hodgkin among others. To understand the process using hematopoietic stem cells, it is necessary to know what exactly a stem cell is. It is an undifferentiated cell, from an embryo, a fetus or even an adult. This cell has the major characteristic of owning self-renewing properties, i.e. it can be renewed on its own. On the other hand, it also possesses capacities of differentiation and proliferation, when it is put into culture, in other words, under conditions that allow it to reproduce, or to multiply if one prefers. Stem cells can be obtained from the bone marrow but also from the blood taken from the inside of a vein, or from the umbilical cord. As far as the blood of the latter is concerned, it is taken after having made a clamping of the cord. It has the advantage of being rich in stem cells, with a great capacity for renewal, and proliferation, provided that these are stimulated by substances such as laboratory cytokines (in vitro). It is also possible to conserve these hematopoietic stem cells by causing them to undergo a cryopreservation (cold preservation). Conservation can last for several years. Due to the immaturity of the newborn's immune system, the risk of acutely-shaped graft-to-host disease is decreased for cord blood, and for the bone marrow from which T cells are removed.


Complications of the disease complications likely to occur during non-Hodgkin malignant lymphomas are as follows:

It is possible to see a gradual invasion of all the lymphatic organs. The lymphomas of the gastrointestinal tract are characterized by a location outside the lymph nodes. This is the case among other things with malignant lymphoma of hail.
It is possible to observe an insufficiency of bone marrow functioning with hemolytic anemia (accompanied by a burst of red blood cells), of an autoimmune nature (the patient produces antibodies against his own constituents), a Jaundice and neurological disorders.